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Life sciences
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» Basic Biological and Medical
Research
» Microbiology, Virology and Immunology
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Natural sciences
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» Biological Chemistry and Food Chemistry
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Researchers with cooperation |
| Institution |
City |
Category |
Country of origin |
| Prof. Beat Ernst / Universität Basel |
Basel |
University abroad |
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| Prof. Mark von Itzstein / Griffith University |
Gold Coast |
University abroad |
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| Prof. Paul Crocker / University Dundee |
Dundee |
University abroad |
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| Prof. Kathrin Mädler / Universität Bremen |
Bremen |
University Germany |
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| Prof. Lars Nitschke / Universität Erlangen |
Erlangen |
University Germany |
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| Prof. Jonathan Andrew Nok / Ahmadu Bello University |
Zaria |
University abroad |
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| Prof. Mohammed M. Mamman / Nigerian Institute for Trypanosomiasis Research |
Kaduna |
Research Center abroad |
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| Prof. Daniel Achukwi / IRAD |
Yaounde |
Research Center abroad |
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| Dr. Antje Hebestreit / BIPS |
Bremen |
Leibniz Association |
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| Prof. Wolfgang Ahrens / BIPS |
Bremen |
Leibniz Association |
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| Prof. Ralf Dringen / Universität Bremen |
Bremen |
University Germany |
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| Prof. Siva Kumar Nadimpalli /University Hyderabad |
Hyderabad |
University abroad |
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| Dr. Martin K Wild / MPI Molekulare Biomedizin |
Münster |
Max Planck Society |
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| Prof. Ulrich Kulozik / TU München |
Weihenstephan |
University Germany |
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| Dr Izabella Brand / Universität Oldenburg |
Oldenburg |
University Germany |
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| Prof. Bernd Meyer / Universität Hamburg |
Hamburg |
University Germany |
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| Prof. Thomas Peters / Universität Lübeck |
Lübeck |
University Germany |
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| Prof. Makoto Kiso / Gifu University |
Gifu |
University abroad |
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Most significant projects |
| Code |
Indication  |
Indication  |
Cooperation partners |
Funding sources/agencies |
Term |
| Bestimmung bioaktiver Glycoverbindungen |
Innovative Verfahren zur Bestimmung und Anreicherung bioaktiver Glykoverbindungen aus Milch für die Entwicklung von prebiotischen Lebensmitteln |
Innovative process for the detection and enrichment of biologically active glycocompounds from milk for the develpoment of prebiotic food |
GALAB Technologies GmbH Milupa GmbH, Numico Research Germany Technische Universität München, Lehrstuhl für Lebensmittelverfahrenstechnik und Molkereitechnologie |
Drittmittel: BMBF, GALAB |
2005 - 2008 |
| Siglecs bei Virusinfektionen |
Die Rolle von Siglecs bei Virusinfektionen |
The role of siglecs in viral infections |
Prof. Reinhard Brossmer, Universität Heidelberg Prof. Lars Nitschke, Universität Erlangen Prof. Thomas Peters, Universität Lübeck Prof. Bernd Meyer, Universität Hamburg Prof. Beat Ernst, Universität Basel, Schweiz Prof. Nicolai Bovin, Shemiakin-Insti |
Drittmittel: Tönjes-Vagt-Stiftung |
2005 - 2009 |
| Charakterisierung von Trans-Sialidase |
Expression und Charakterisierung rekombinanter Trans-Sialidase aus Trypanosoma congolense |
Expression and characterization of recombinant trans-sialidase from Trypanosoma congolense |
Prof. A.J. Nok, Zaria, Nigeria |
Drittmittel: DFG Fa. Milupa |
2005 - 2010 |
| Sialylierung von Glykokonjugaten |
Funktionen und Modifikationen sialylierter Milch-Glykokonjugate |
Functions and modifications of sialylated milk glycoconjugates |
Milupa Research, Friedrichsdorf |
Drittmittel: Milupa Research, Friedrichsdorf |
2004 - 2005 |
| Wechselwirkung des Siglecs CD22 |
Wechselwirkung des Siglecs CD22 mit Glykokonjugaten und resultierende biologische Funktionen |
Interaction of Siglec-2 (CD22) with glycoconjugates and resulting biological functions |
Prof. Nitschke, Lars, Universität Erlangen Milupa Research, Friedrichsdorf |
Drittmittel: Zentrum für Biotechnologie und Ernährung |
2003 - 2004 |
| MAG interactions with sialylated ligands |
Konformationelle Kontrolle der Präsentation von geladenen, hydrophilen und hydrophoben Gruppen bei Kohlenhydrat-MAG Interaktionen im zentralen Nervensystem |
Conformational control of the presentation of charged, hydrophilic, and hydrophobic groups in carbohydrate-MAG interactions in the central nervous system |
Beat Ernst, Basel Bernd Meyer, Hamburg (Koordinator) Thomas Peters, Lübeck |
Drittmittel: Volkswagenstiftung |
2001 - 2009 |
| Evolution der Sialylierung |
Klonierung und Charakterisierung von Siglecs und Sialyltransferasen aus Fischen und Echinodermanten |
Cloning and characterisation of siglces and sialyltransferases from fish and echinoderms |
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Universität Bremen |
2001 - 2004 |
| Modifikation von HDGF |
Post-translationale Modifikationen von Hepatoma-derived Growth Factor und verwandten Proteinen |
Post-translational modification of hepatoma-derived growth factor and related proteins |
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Universität Bremen |
2001 - 2010 |
| Bindungspartner von MAG |
Isolierung und Charakterisierung neuronaler Bindungspartner des Myelin-assoziierten Glykoproteins |
Isolation and Characterisation of neuronal binding partners of the myelin-associated glycoprotein (MAG) |
Reinhard Brossmer Melitta Schachner |
Drittmittel: Deutsche Forschungsgemeinschaft |
1999 - 2002 |
| Molecular recognition by siglecs |
Molekulare Erkennungsmechanismen bei Siglecs |
Molecular recognition of sialylated ligands by sialoadhesin and related proteins |
Reinhard Brossmer, Heidelberg Paul R. Crocker, Dundee, UK Marie Filbin, New York, USA Yvonne Jones, Oxford, UK Lars Nitschke, Würzburg Anton van der Merwe, Oxford, UK |
Drittmittel: Human Frontier Science Program |
1998 - 2001 |
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Most significant Publications |
C-4 Modified Sialosides Enhance Binding to Siglec-2 (CD22): Towards Potent Siglec Inhibitors for Immunoglycotherapy
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Type |
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Monograph |
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Biochemical characterization of trans-sialidase TS1 variants from Trypanosoma congolense
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Type |
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Article |
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The ligand-binding domain of CD22 is needed for inhibition of the BCR signal, as demonstrated by a novel human CD22-specific inhibitor compound
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Type |
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Article |
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Molecular basis for the generation in pigs of influenza A viruses with pandemic potential
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Type |
| Author(s) | T. Ito, J. N. S. S. Couceiro, S. Kelm, L. G. Baum, S. Krauss, M. R. Castrucci, I. Donatelli, H. Kida, J. C. Paulson, R. G. Webster, Y. Kawaoka | | Year | 1998 | | In | J. Virol. | | Year | 72 | | Issue | 9 | | Pages | 7367-7373 | | Link zu Volltext |  http://jvi.asm.org/content/72/9/7367.long |
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Article |
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Sialoadhesin, MAG and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily
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Type |
| Author(s) | S. Kelm, A. Pelz, R. Schauer, M. T. Filbin, S. Tang, M.-E. de Bellard, R. L. Schnaar, J. A. Mahoney, A. Hartnell, P. Bradfield, P. R. Crocker | | Year | 1994 | | In | Curr. Biol. | | Year | 4 | | Issue | 11 | | Pages | 965-972 | | Doi | 10.1016/S0960-9822(00)00220-7 | | Link zu Volltext | http://www.cell.com/current-biology/abstract/S0960-9822%2800%2900220-7 |
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Sialic acids in cellular interactions and signal transduction (sialic acid-recognising proteins;
evolution of sialic acid metabolism;
role of trans-sialidases for the transmission of Trypanosomes;
lectins in biomineralisation (perlucin).
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